Biostatistics Department

1. Zanti M, …, Michailidou K. Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification. Nat Commun. 2025;16(1):4852. doi:10.1038/s41467-025-59979-6
2. Sahu S, Galloux M, Southon E, et al. Saturation genome editing-based clinical classification of BRCA2 variants. Nature. 2025;638(8050):538-545. doi:10.1038/s41586-024-08349-1
3. Yiangou K., …, Michailidou K. Differences in polygenic score distributions in European ancestry populations: implications for breast cancer risk prediction, Breast Cancer Research. 2024 Dec 29; 26, 189. doi:10.1186/s13058-024-01947-x
4. Zanti M., … Michailidou K. A Likelihood Ratio Approach for Utilizing Case-Control Data in the Clinical Classification of Rare Sequence Variants: Application to BRCA1 and BRCA2. Human Mutation, vol. 2023, 9961341, doi:10.1155/2023/9961341
5. Zanti M, … Michailidou K. Multi-gene panel testing and association analysis in Cypriot breast cancer cases and controls. Front Genet. 2023;14:1248492. Published 2023 Sep 18. doi:10.3389/fgene.2023.1248492
6. O’Mahony D, … Michailidou K. Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2. Br J Cancer. 2023;128(12):2283-2294. doi:10.1038/s41416-023-02263-5
7. Pashayan N, Easton DF, Michailidou K. Polygenic risk scores in cancer screening: a glass half full or half empty? Lancet Oncol. 2023;24(6):579-581. doi:10.1016/S1470-2045(23)00217-6
8. Yiangou K, Kyriacou K, Kakouri E, Marcou Y, Panayiotidis MI, Loizidou MA, Hadjisavvas A, Michailidou K. Combination of a 15-SNP Polygenic Risk Score and Classical Risk Factors for the Prediction of Breast Cancer Risk in Cypriot Women. Cancers. 2021; 13(18):4568. doi:10.3390/cancers13184568
9. Michailidou, K. et al. Association analysis identifies 65 new breast cancer risk loci. Nature 551, 92-94 (2017). doi:10.1038/nature24284
10. Michailidou, K. et al. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet 45, 353-61, 361e1-2 (2013). doi:10.1038/ng.2563

Full list of publications can be found here: