0002.jpg)
Blood Disorder Genetics and Thalassemia Department
Gene Editing and Therapy
(Investigators Carsten W Lederer, Petros Patsali, Panayiota L Papasavva, Marios Phylactides)
Establishment of novel gene therapy approaches for hemoglobinopathies and other hematological diseases, based on genome editing and gene addition techniques, to address:
- β-Thalassemia
- Sickle cell disease
- α-Thalassemia
- Iron homeostasis disorders
Development of advanced therapies for patients in Cyprus in collaboration with international centers and companies
Exploration of novel vectors for delivery and of novel tools for targeted DNA modification, to enable translational research of therapies, biomarkers and gene function